{"id":198,"date":"2022-05-20T11:13:28","date_gmt":"2022-05-20T09:13:28","guid":{"rendered":"https:\/\/web.umons.ac.be\/seco\/?page_id=198"},"modified":"2022-05-20T11:13:28","modified_gmt":"2022-05-20T09:13:28","slug":"mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes","status":"publish","type":"page","link":"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/","title":{"rendered":"Mathematical modeling and predictive control of hot-melt extrusion processes"},"content":{"rendered":"<p>Hot melt extrusion is a process combining heat and pressure to melt a polymer and forcing it through an orifice in a continuous process.<\/p>\n<p>This process is one of the most popular technology for processing plastic, rubber, and food and has more recently been applied to the healthcare industry where it is used to manufacture mix active pharmaceutical ingredients (APIs) with polymers.<\/p>\n<p>We have conducted research in the latter application area:<\/p>\n<ul>\n<li>mathematical modeling, parameter identification from residence time distributions and screw torque evolution, and numerical simulation<\/li>\n<\/ul>\n<p>Model predictive control of the API concentration<\/p>\n<h3>Further reading<\/h3>\n<p>A review of dynamic models of hot-melt extrusion<br \/>\nby Jonathan Grimard, Laurent Dewasme, and Alain Vande Wouwer<br \/>\nProcesses, 2016, vol. 4, no 2, p. 19<\/p>\n<p><a href=\"https:\/\/doi.org\/10.3390\/pr4020019\">https:\/\/doi.org\/10.3390\/pr4020019<\/a><\/p>\n<p><a href=\"https:\/\/www.mdpi.com\/2227-9717\/4\/2\/19\">https:\/\/www.mdpi.com\/2227-9717\/4\/2\/19<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hot melt extrusion is a process combining heat and pressure to melt a polymer and forcing it through an orifice in a continuous process. This process is one of the most popular technology for processing plastic, rubber, and food and has more recently been applied to the healthcare industry where it is used to manufacture [&hellip;]<\/p>\n","protected":false},"author":95,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-198","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mathematical modeling and predictive control of hot-melt extrusion processes - Service \/ FPMS - Syst\u00e8mes, Estimation, Commande et Optimisation<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mathematical modeling and predictive control of hot-melt extrusion processes - Service \/ FPMS - Syst\u00e8mes, Estimation, Commande et Optimisation\" \/>\n<meta property=\"og:description\" content=\"Hot melt extrusion is a process combining heat and pressure to melt a polymer and forcing it through an orifice in a continuous process. This process is one of the most popular technology for processing plastic, rubber, and food and has more recently been applied to the healthcare industry where it is used to manufacture [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/\" \/>\n<meta property=\"og:site_name\" content=\"Service \/ FPMS - Syst\u00e8mes, Estimation, Commande et Optimisation\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/\",\"url\":\"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/\",\"name\":\"Mathematical modeling and predictive control of hot-melt extrusion processes - Service \/ FPMS - Syst\u00e8mes, Estimation, Commande et Optimisation\",\"isPartOf\":{\"@id\":\"https:\/\/web.umons.ac.be\/seco\/#website\"},\"datePublished\":\"2022-05-20T09:13:28+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/web.umons.ac.be\/seco\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Mathematical modeling and predictive control of hot-melt extrusion processes\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/web.umons.ac.be\/seco\/#website\",\"url\":\"https:\/\/web.umons.ac.be\/seco\/\",\"name\":\"Service \/ FPMS - Syst\u00e8mes, Estimation, Commande et Optimisation\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/web.umons.ac.be\/seco\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Mathematical modeling and predictive control of hot-melt extrusion processes - Service \/ FPMS - Syst\u00e8mes, Estimation, Commande et Optimisation","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/web.umons.ac.be\/seco\/mathematical-modeling-and-predictive-control-of-hot-melt-extrusion-processes\/","og_locale":"fr_FR","og_type":"article","og_title":"Mathematical modeling and predictive control of hot-melt extrusion processes - Service \/ FPMS - Syst\u00e8mes, Estimation, Commande et Optimisation","og_description":"Hot melt extrusion is a process combining heat and pressure to melt a polymer and forcing it through an orifice in a continuous process. 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