{"id":116,"date":"2020-10-13T14:04:00","date_gmt":"2020-10-13T12:04:00","guid":{"rendered":"https:\/\/web.umons.ac.be\/smos\/?p=116"},"modified":"2022-05-23T14:28:14","modified_gmt":"2022-05-23T12:28:14","slug":"new-paper-on-the-analysis-of-isomeric-homo-and-copolymers-by-ion-mobility-mass-spectrometry","status":"publish","type":"post","link":"https:\/\/web.umons.ac.be\/smos\/2020\/10\/13\/new-paper-on-the-analysis-of-isomeric-homo-and-copolymers-by-ion-mobility-mass-spectrometry\/","title":{"rendered":"New paper on the analysis of isomeric homo and copolymers by ion mobility mass spectrometry"},"content":{"rendered":"
\"New
New paper on the analysis of isomeric homo and copolymers by ion mobility mass spectrometry<\/figcaption><\/figure>\n

In this work, we evaluate whether a relationship exists between the primary structures of synthetic homo and copolymers and their secondary structures as gaseous ions. IMS\u2212MS experiments are further complemented by MD simulations. To highlight the effectiveness of IMS separation, we selected isomeric homo and copolymers made of lactide (LA) and propiolactone (PL) units. In this way, the mass analysis becomes useless since isomeric comonomer sequences can coexist for any given chain length. An UPLC method is implemented in the workflow to successfully separate all PL\u2212LA comonomer sequences before infusion in the IMS\u2212MS instrument. The analysis of doubly charged copolymers shows that the comonomer sequence has an impact on the IMS response. However, this only holds for copolymer ions with precise sizes and charge states, and this is therefore not a rule of thumb.<\/p>\n

https:\/\/pubs.acs.org\/doi\/10.1021\/jasms.0c00352<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

In this work, we evaluate whether a relationship exists between the primary structures of synthetic homo and copolymers and their secondary structures as gaseous ions. IMS\u2212MS experiments are further complemented by MD simulations.<\/p>\n","protected":false},"author":157,"featured_media":117,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-116","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recherche"],"yoast_head":"\nNew paper on the analysis of isomeric homo and copolymers by ion mobility mass spectrometry - Service \/ FS - Synth\u00e8se et Spectrom\u00e9trie de Masse Organiques<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/web.umons.ac.be\/smos\/2020\/10\/13\/new-paper-on-the-analysis-of-isomeric-homo-and-copolymers-by-ion-mobility-mass-spectrometry\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New paper on the analysis of isomeric homo and copolymers by ion mobility mass spectrometry - Service \/ FS - Synth\u00e8se et Spectrom\u00e9trie de Masse Organiques\" \/>\n<meta property=\"og:description\" content=\"In this work, we evaluate whether a relationship exists between the primary structures of synthetic homo and copolymers and their secondary structures as gaseous ions. IMS\u2212MS experiments are further complemented by MD simulations.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/web.umons.ac.be\/smos\/2020\/10\/13\/new-paper-on-the-analysis-of-isomeric-homo-and-copolymers-by-ion-mobility-mass-spectrometry\/\" \/>\n<meta property=\"og:site_name\" content=\"Service \/ FS - Synth\u00e8se et Spectrom\u00e9trie de Masse Organiques\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-13T12:04:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-05-23T12:28:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/web.umons.ac.be\/app\/uploads\/sites\/80\/2022\/05\/2020-10-13_Q-Duez.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1448\" \/>\n\t<meta property=\"og:image:height\" content=\"773\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Eric Weverbergh\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Eric Weverbergh\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/web.umons.ac.be\/smos\/2020\/10\/13\/new-paper-on-the-analysis-of-isomeric-homo-and-copolymers-by-ion-mobility-mass-spectrometry\/\",\"url\":\"https:\/\/web.umons.ac.be\/smos\/2020\/10\/13\/new-paper-on-the-analysis-of-isomeric-homo-and-copolymers-by-ion-mobility-mass-spectrometry\/\",\"name\":\"New paper on the analysis of isomeric homo and copolymers by ion mobility mass spectrometry - 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