Toutes les nouvelles

  • Poison or Potion: Effects of Sunflower Phenolamides on Bumble Bees and Their Gut Parasite
    Recherche

    Poison or Potion: Effects of Sunflower Phenolamides on Bumble Bees and Their Gut Parasite

    24 mai 2022
    In this work, we tested the impacts of sunflower phenolamides on healthy and parasite infected buff-tailed bumble bees. Expectedly, sunflower pollen had harmful consequences on bumble bee development but surprisingly, it did not alter parasite load. By contrast, sunflower phenolamides had milder effects on bumble bee development but unexpectedly increased parasite load.
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations, Dr Saintmont !
    Alumni

    Congratulations, Dr Saintmont !

    10 février 2022
    On Wednesday February 9, Fabrice SAINTMONT has defended his PhD thesis entitled “Synthetic macromolecules and nucleic acids : experimental and theoretical investigation of dendriplex structures”
    Synthèse et Spectrométrie de Masse Organiques
  • On the Conformation of Anionic Peptoids in the Gas Phase
    Recherche

    On the Conformation of Anionic Peptoids in the Gas Phase

    02 février 2022
    Although N-(S)-phenylethyl peptoids are known to adopt helical structures in solutions, the corresponding positively charged ions lose their helical structure during the transfer from the solution to the gas phase due to the so-called charge solvation effect. We, here...
    Synthèse et Spectrométrie de Masse Organiques
  • New paper published in Mass Spectrometry Review, “Gas-phase structure of polymer ions: Tying together theoretical approaches and ion mobility spectrometry” by Quentin, Sebastien, Thomas, Jérôme, Pascal and Julien
    Recherche

    New paper published in Mass Spectrometry Review, “Gas-phase structure of polymer ions: Tying together theoretical approaches and ion mobility spectrometry” by Quentin, Sebastien, Thomas, Jérôme, Pascal and Julien

    23 novembre 2021
    An increasing number of studies take advantage of ion mobility spectrometry (IMS) coupled to mass spectrometry (IMS-MS) to investigate the spatial structure of gaseous ions. Synthetic polymers occupy a unique place in the field of IMS-MS. Indeed...
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations, Dr Cauchie !
    Alumni

    Congratulations, Dr Cauchie !

    26 octobre 2021
    On Tuesday October 26, Gaela CAUCHIE has defended her PhD thesis entitled “Profilage chimique de la biomasse microalgale par MS et RMN : étude de cas avec Microchloropsis gaditana ” at the Université de Reims Champagne-Ardenne. The thesis was co-directed by Prof Jean-Hugues Renault (URCA) and Prof Pascal Gerbaux (UMONS) in the frame of the ALPO project granted by the Interreg program.
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations, Dr HOYAS !
    Alumni

    Congratulations, Dr HOYAS !

    24 septembre 2021
    On Friday September 24, Sébastien HOYAS has defended his PhD thesis entitled “Characterization and exploitation of peptoid secondary structures: a synergetic experimental and computational approach ” at the University of Mons.
    Synthèse et Spectrométrie de Masse Organiques
  • New paper published in Journal of Medicinal Chemistry in Collaboration with Prof Stephane Vincent from UNamur
    Recherche

    New paper published in Journal of Medicinal Chemistry in Collaboration with Prof Stephane Vincent from UNamur

    30 août 2021
    Pseudomonas aeruginosa (P.A.) is a human pathogen belonging to the top priorities for the discovery of new therapeutic solutions. Its propensity to generate biofilms strongly complicates the treatments required to cure P.A. infections. Herein, we describe the synthesis of a series of novel rotaxanes composed of a central galactosylated pillar[5]arene, a tetrafucosylated dendron, and a tetraguanidinium subunit. Besides the high affinity of the final glycorotaxanes for the two P.A. ...
    Synthèse et Spectrométrie de Masse Organiques
  • Just accepted paper: peptoids and hydrogen bonds in gas phase
    Recherche

    Just accepted paper: peptoids and hydrogen bonds in gas phase

    09 juillet 2021
    We recently reported a joint experimental and theoretical study of peptoid ions bearing (S)-N-1-phenylethyl side chains. In this study, we demonstrated that the gas phase conformation, probed by ion mobility mass spectrometry, was different from the solution phase conformation (loop vs. helix) because the charge, mandatory for mass spectrometry analysis, must be stabilized and causes the backbone to wrap around to maximize the ion-dipole interactions.
    Synthèse et Spectrométrie de Masse Organiques
  • New paper published in Algal Research on the analysis of the bead milling impact on the lipid profile of the microalgae Microchloropsis gaditana by LC-MS
    Recherche

    New paper published in Algal Research on the analysis of the bead milling impact on the lipid profile of the microalgae Microchloropsis gaditana by LC-MS

    09 juillet 2021
    Liquid chromatography – mass spectrometry (LC-MS) experiments were used to qualitatively and semi-quantitatively monitor the impact of bead milling and the influence of the nature of the extraction solvents, Bligh and Dyer (B&D) versus n-heptane, on the composition of the structural lipids extracted from the microalgae Microchloropsis gaditana.
    Synthèse et Spectrométrie de Masse Organiques
  • New paper in Collaboration with the Laboratory of Polymeric and Composite Materials (UMONS)
    Recherche

    New paper in Collaboration with the Laboratory of Polymeric and Composite Materials (UMONS)

    08 juillet 2021
    Recent advances in catalysis enriched the toolbox to prepare well-defined polyester materials such as polylactide (PLA). Herein, we report the use of crown ethers to speed up the polymerization of L-lactide (L-LA) initiated by an exogenous alcohol and catalyzed by potassium acetate (KOAc).
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations, Dr BOUANATI !
    Alumni

    Congratulations, Dr BOUANATI !

    16 mars 2021
    On Thursday march 11, Tiffani BOUANATI has defended her PhD thesis entitled “Production, characterization and valorization of the polysaccharidic fraction of  macroalgae and microalgae”.
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations, Dr Delpierre !
    Alumni

    Congratulations, Dr Delpierre !

    02 novembre 2020
    On Friday October 30, Sébastien DELPIERRE has defended his PhD thesis entitled “Self-Healable and Recyclable Polymer Networks Based on Dynamic Covalent Boroxine Chemistry”.
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations, Dr Duez !
    Alumni

    Congratulations, Dr Duez !

    29 septembre 2020
    On Friday September 25, Quentin DUEZ has defended his PhD thesis entitled “Gas-Phase Structure of Polymer Ions : Ionization, Relaxation, and Implications for Structural Characterization”.
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations, Dr Colson !
    Alumni

    Congratulations, Dr Colson !

    28 septembre 2020
    On Friday September 18, Emmanuel Colson - Manu - has defended his PhD thesis entitled “Green Waste Valorization : tuning the biological properties of horse chestnut and quinoa husk saponins by molecular engineering”.
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations Dr Liénard
    Alumni

    Congratulations Dr Liénard

    22 septembre 2020
    On Friday September 11, Romain Liénard, PhD student at the Organic Synthesis Lab (S²MOs) and Polymer Lab (SMPC), has defended his PhD thesis entitled “Original Cyclo-based Macrostructures: Elaboration and Characterization” under the joint supervision of Olivier Coulembier and Julien De Winter.
    Synthèse et Spectrométrie de Masse Organiques
  • New paper published in collaboration with Prof. Angela Scala (University of Messina)
    Recherche

    New paper published in collaboration with Prof. Angela Scala (University of Messina)

    21 septembre 2020
    We report the synthesis, characterization and biological profile of new bis-triazoled cyclo-(polylactide)s functionalized with folic acid (c-PLA-FA) or rhodamine (c-PLA-Rhod), obtained by an optimized combination of ROP and “click” chemistry reactions.
    Synthèse et Spectrométrie de Masse Organiques
  • New article on microwave-assisted depolymerization of polysaccharides by Tiffani Bouanati
    Recherche

    New article on microwave-assisted depolymerization of polysaccharides by Tiffani Bouanati

    21 septembre 2020
    Algae biomass is nowadays considered as a unique reservoir of a huge variety of different molecules, such as lipids, carbohydrates, proteins and secondary metabolites, awaiting development in various fields. In particular, the valorization of the algae polysaccharide content is still in its infancy and intense research activity is starting to appear.
    Synthèse et Spectrométrie de Masse Organiques
  • New article in Molecules on the structure/activity relationship of saponins by Emmanuel Colson
    Recherche

    New article in Molecules on the structure/activity relationship of saponins by Emmanuel Colson

    09 avril 2020
    In this paper, we are interested to Chenopodium quinoa seed, a staple food widely used around the world due to high nutritive values and the resistance of the crop to drought, cold and hard climate. However, the husk represents a waste that contains huge amounts of saponins that certainly deserve valorization. ...
    Synthèse et Spectrométrie de Masse Organiques
  • New paper on the effects of Electrospray Ionization mechanisms and structural relaxation for polylactide ions.
    Recherche

    New paper on the effects of Electrospray Ionization mechanisms and structural relaxation for polylactide ions.

    11 février 2020
    In the present study, we use this approach to investigate the release of polylactide (PLA) ions from water/acetonitrile ESI droplets. We found that cationized gaseous PLA ions can be formed via various competing pathways. Some MD runs showed extrusion and subsequent separation of polymer chains from the droplet, as envisioned by the chain ejection model (CEM). ...
    Synthèse et Spectrométrie de Masse Organiques
  • Just accepted paper: On the Helicity of Peptoids in the Gas Phase
    Recherche

    Just accepted paper: On the Helicity of Peptoids in the Gas Phase

    22 janvier 2020
    We demonstrate with the help of theoretical modelling that peptoids actually adopt a loop-like geometry in the gas phase even though the measured collision cross sections are very similar to those expected for helices. ...
    Synthèse et Spectrométrie de Masse Organiques
  • Congrats, Dr Halin !
    Alumni

    Congrats, Dr Halin !

    02 décembre 2019
    On Friday November 29, Emilie Halin has defended her PhD thesis entitled “On the Mass Spectrometry Characterization of peptoids, a new class of biomimetic synthetic polymers with tunable secondary structures”.
    Synthèse et Spectrométrie de Masse Organiques
  • New paper on the relative quantification of architectural isomeric polymers
    Recherche

    New paper on the relative quantification of architectural isomeric polymers

    15 novembre 2019
    In this work, we are investigating the suitability of Ion Mobility Spectrometry-Mass Spectrometry (IMS) for the quantification of two isomers. A cyclic poly(L-lactide) is prepared through photodimerization of its linear homologue. ...
    Synthèse et Spectrométrie de Masse Organiques
  • Recherche

    Functional Polyethylene (PE) and PE-Based Block Copolymers by Organometallic-Mediated Radical Polymerization

    07 novembre 2019
    in the present work, the controlled radical homopolymerization of ethylene via organometallic-mediated radical polymerization (OMRP) using a cobalt complex as controlling agent was investigated. For the first time, block copolymers composed of ethylene and polar vinyl monomers, e.g. poly(vinyl acetate)-b-polyethylene (PVAc-b-PE) and poly(ethylene vinyl acetate)-b-polyethylene (EVA-b-PE) were prepared. ...
    Synthèse et Spectrométrie de Masse Organiques
  • Recherche

    New paper in Collaboration with Guy Koeckelberghs

    21 octobre 2019
    In this article we investigate association of the Ni-catalyst during Kumada catalyst transfer condensative polymerization (KCTCP) and hypothesize that when adding a para-phenylene monomer to a living thiophene block to synthesize poly(thiophene)-b-poly(para-phenylene), an equilibrium exist between the incorporation of the para-phenylene monomer and the trapping of the Ni-catalyst by association with the thiophene block. ...
    Synthèse et Spectrométrie de Masse Organiques
  • New paper on Ion Mobility for Natural Product Analysis in collaboration with Waters UK
    Recherche

    New paper on Ion Mobility for Natural Product Analysis in collaboration with Waters UK

    11 septembre 2019
    In the present paper, it has been shown that ion mobility experiments together with liquid chromatography separation can be utilized for the structural characterization of stereoisomeric and regioisomeric saponins. Saponins presenting isomeric side chains, such as tiglic and angelic acid residues, can be distinguished by recording the Arrival Time Distributions (ATD), provided that high resolution ion mobility separation is used. ...
    Synthèse et Spectrométrie de Masse Organiques
  • One Step Further in the Characterization of Synthetic Polymers by Ion Mobility Mass Spectrometry: Evaluating the Contribution of End-groups
    Recherche

    One Step Further in the Characterization of Synthetic Polymers by Ion Mobility Mass Spectrometry: Evaluating the Contribution of End-groups

    30 avril 2019
    Several families of polymers possessing various end-groups are characterized by ion mobility mass spectrometry (IMMS). A significant contribution of the end-groups to the ion collision cross section (CCS) is observed, although their role is neglected in current fitting models described in literature. ...
    Synthèse et Spectrométrie de Masse Organiques
  • New paper in Collaboration with Sébastien Clément from the University of Montpellier on the synthesis of conjugated semiconducting polymers.
    Recherche

    New paper in Collaboration with Sébastien Clément from the University of Montpellier on the synthesis of conjugated semiconducting polymers.

    30 avril 2019
    A poly(3-hexylthiophene)-block-perfluoropolyether-block-poly(3-hexylthiophene) (P3HT-b-PFPE-b-P3HT) triblock copolymer was synthesized by copper(I)-catalyzed alkyne–azide cycloaddition. The copolymer was unequivocally characterized by size exclusion chromatography, mass spectrometry and nuclear magnetic resonance (NMR). ...
    Synthèse et Spectrométrie de Masse Organiques
  • New paper on the synthesis of poymers for organic radical batteries.
    Recherche

    New paper on the synthesis of poymers for organic radical batteries.

    30 avril 2019
    End-functionalized poly(3-hexylthiophene) (P3HT) and poly(2,2,6,6-tetramethylpiperidinyloxy-4-yl methacrylate) (PTMA) were synthesized using controlled polymerization techniques and linked together to lead to a diblock copolymer structure via click cycloaddition.
    Synthèse et Spectrométrie de Masse Organiques
  • Irène Semay and Quentin Duez Awarded During the 12th Meeting of the Young Chemists of the Royal Society of Chemistry
    Prix, bourses et distinction

    Irène Semay and Quentin Duez Awarded During the 12th Meeting of the Young Chemists of the Royal Society of Chemistry

    30 avril 2019
    The 12th Meeting of the Young Chemists of the Royal Society of Chemistry took place on April 26th in Brussels. During this meeting, Irène Semay (S²MOs – Center on the picture) and Quentin Duez (S²MOs/CMN – Left on the picture) were respectively awarded of the Best Poster Prize and the Jean-Claude Braekman Prize for the best oral communication describing his collaboration with a foreign lab!
    Synthèse et Spectrométrie de Masse Organiques
  • New paper in the frame of the ALPO Interreg project
    Recherche

    New paper in the frame of the ALPO Interreg project

    30 avril 2019
    Here, we report the synthesis of a novel diester bearing a pendant lactam unit from methyl levulinate and aspartic acid. The palladiumcatalyzed reductive amination/cyclization sequence was carefully optimized to afford the diacid with high yield (>95 %).
    Synthèse et Spectrométrie de Masse Organiques
  • New paper in the frame of the ALPO Interreg project
    Recherche

    New paper in the frame of the ALPO Interreg project

    20 novembre 2018
    The S2MOs laboratory is involved in the ALPO Interreg project that aims at producing building blocks for polymer preparation starting from the micro-algae biomass....
    Synthèse et Spectrométrie de Masse Organiques
  • New paper on spinochrome pigments by Lola Brasseur
    Recherche

    New paper on spinochrome pigments by Lola Brasseur

    08 novembre 2018
    Tuleariocaris holthuisi and Arete indicus are two ectocommensal shrimps closely associated with the tropical sea urchin Echinometra mathaei. This study provides a comparison of these two E. mathaei symbiotic crustaceans and particularly focuses on the relationship between T....
    Synthèse et Spectrométrie de Masse Organiques
  • New paper on Peptoids by Emilie Halin
    Recherche

    New paper on Peptoids by Emilie Halin

    05 novembre 2018
    In the present paper, we submitted protonated tailor-made peptoids to (energy-resolved) collision-induced dissociation experiments to investigate the side-chain loss reaction mechanisms....
    Synthèse et Spectrométrie de Masse Organiques
  • New paper in Collaboration with Olivier Coulembier
    Recherche

    New paper in Collaboration with Olivier Coulembier

    05 novembre 2018
    In this manuscript, a novel solvent-free and organocatalyzed ring-opening (co)polymerization (ORO(c)P) method utilizing benzoic acid(BA) as simple thermostable carboxylic acid-type catalyst is proposed to not only produce structurally well-defined aliphatic homopolyesters derived from L-lactide (L-LA) and Ɛ-caprolactone (CL), but also and, unexpectedly, statistical copolyesters based on the two monomer units. RO(c)P reactions were conducted in bulk in a  temperature range of 155-180°C, in presence of alcohols as initiators.
    Synthèse et Spectrométrie de Masse Organiques
  • New paper in Collaboration with Guy Koeckelberghs
    Recherche

    New paper in Collaboration with Guy Koeckelberghs

    22 octobre 2018
    In this manuscript, the new conjugated poly(4,4-bis(2- ethylhexyl)cyclopentadithiophene-alt-p-phenylene) (PCPDTPP) has been synthesized in a controlled way via catalyst transfer condensative polymerization (CTCP) of the corresponding bi-aryl monomer....
    Synthèse et Spectrométrie de Masse Organiques
  • Congratulations Dr Decroo !
    Alumni

    Congratulations Dr Decroo !

    15 octobre 2018
    On Friday October 11, Corentin Decroo, M.Sc., successfully presented his doctorate results to a jury composed of Professors Isabelle Fournier (Lille), Catherine Lavaud (Reims), Pierre Duez, Jérôme Cornil, Roberto Lazzaroni, Patrick Flammang and Pascal Gerbaux.
    Synthèse et Spectrométrie de Masse Organiques
  • New paper in Collaboration with Guy Koeckelberghs
    Recherche

    New paper in Collaboration with Guy Koeckelberghs

    15 octobre 2018
    This work presents the controlled synthesis and characterization of star shaped poly(3-alkylthiophene) (P3AT). The perfect control over the synthesis was mostly confirmed by MALDI mass spectrometry.  The originality of this study was the synthesis of controlled star-shaped polymers (P3AT)  presenting the formation of a strong (chiral) supramolecular organization into fibers, different and stronger obtained with the linear P3ATs...
    Synthèse et Spectrométrie de Masse Organiques
  • New Paper on Ion Mobility by Quentin Duez
    Recherche

    New Paper on Ion Mobility by Quentin Duez

    08 octobre 2018
    In this work, we probed the gas phase structure of alkylamines/Ag+ complexes by ion mobility mass spectrometry and tandem mass spectrometry with the support of DFT-level calculations....
    Synthèse et Spectrométrie de Masse Organiques
  • International Mass Spectrometry Conference 2018 - Poster from Halin Emilie
    Conférences & Colloques

    International Mass Spectrometry Conference 2018 - Poster from Halin Emilie

    11 septembre 2018
    Peptoids are an emergent class of biosynthetic foldamers finding applications in area such as chiral resolution or catalysis [10-11]. CD and NMR are the common techniques used to decipher the secondary structures of peptoid oligomers in solution [5-6]. IMMS represents an elegant way to access to the gas-phase structure of ions. ...
    Synthèse et Spectrométrie de Masse Organiques
  • New Paper on Spinochromes by Lola Brasseur
    Recherche

    New Paper on Spinochromes by Lola Brasseur

    04 septembre 2018
    Brasseur et al., Mapping of Spinochromes in the Body of Three Tropical Shallow Water Sea Urchins, Natural Product Communications, just accepted.
    Synthèse et Spectrométrie de Masse Organiques
  • IMSC 2018.
    Conférences & Colloques

    IMSC 2018.

    04 septembre 2018
    Pascal Gerbaux and Luisa Mattoli (Aboca, Italy) have officiated as chair and co-chair of the Natural substances and their complexes” session at the International Conference of Mass Spectrometry, IMSC 2018. This conference was organized in Florence between August 26 and 31 and gathered 1800 attendees from 70 different countries.
    Synthèse et Spectrométrie de Masse Organiques
  • New Paper on Peptoids by Sebastien Hoyas
    Recherche

    New Paper on Peptoids by Sebastien Hoyas

    03 septembre 2018
    We have developed the PEPDROID force field by evaluating a new set of parameters to be incorporated in the original DREIDING force field and applied to (α or β) peptoids bearing different type of side chains.
    Synthèse et Spectrométrie de Masse Organiques
  • BBQ chimistes 2015-2016
    Alumni

    BBQ chimistes 2015-2016

    04 juillet 2017
    BBQ chimistes 2015-2016
    Synthèse et Spectrométrie de Masse Organiques